Quantifying tissue composition is crucial for accurate medical diagnoses. Photoacoustic imaging, which uses pulsed light to generate sound waves from tissue, emerges as a promising technique for tissue quantification. It offers deep imaging capabilities, optical contrast, and acoustic resolution. Its integration with conventional ultrasound imaging leverages structural tissue information...
We report on a hybrid photoacoustic and ultrasound-transmission tomographic system (PAM3). The photoacoustic component has multi-wavelength imaging capability, and implements substantial technical advancements in important hardware and software sub-systems. The ultrasound component enables for the first time, a three-dimensional sound speed map of the breast to be imaged. This map is used in...
Background:
Peripheral nerves play crucial roles in motor and sensory functions, and their clinical imaging typically involves ultrasound and MRI. Ultrasound has limitations due to shallow depth, poor spatial resolution, and operator-dependent acquisition, while MRI is constrained by imaging time and motion artifacts. Ultrasound Computed Tomography (USCT) presents a promising solution for...
Background:
Intracranial soft tissue imaging using traditional ultrasound is a difficult task due to the presence of the skull, which strongly reflects and attenuates the ultrasound signal. To address this problem, we have conducted preliminary research on full waveform inversion (FWI)-based ultrasound computed tomography (USCT) for in vivo human brain imaging.
Material and Method:
We...
Abdominal aortic aneurysms (AAA) are large dilatations of the abdominal aorta, that are typically asymptomatic until a life-threatening rupture occurs. Knowledge of AAA geometry and local mechanical wall parameters using ultrasound is paramount for risk stratification and intervention planning. However, such an assessment is limited by the lateral lumen-wall contrast and resolution of...
