Speaker
Mrs
Elisabeth Fischer-Friedrich
(Excellence Cluster Physics of Life, TU Dresden)
Description
The actin cortex is a thin polymer network beneath the plasma membrane in animal cells. It acts as a mechanical shield of the cell and as a major regulator of cell shape and cell migration. The actin cortex is a complex material with time-dependent viscoelastic mechanical properties. It is further subject to a self-generated active contractile stress and to constituent turnover. I will discuss our measurement results on frequency-dependent cortical viscoelasticity measured by atomic force microscopy. In addition, I will discuss how mechanosensitivity of molecular bonds can affect molecular composition of the cortex and how this mechanosensitivity can be quantified in live cells.
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Primary author
Mrs
Elisabeth Fischer-Friedrich
(Excellence Cluster Physics of Life, TU Dresden)
